HitPredict

Interactor 1: INS (P01308)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32457219, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0030335 - positive regulation of cell migration
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 110 Hs			1 654
+	Hs
		351910 INS_HUMAN (1-110): 3.37e-65: 194: 100.00		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		351903 INS_HUMAN (1-110): 3.37e-65: 194: 100.00		HS71A_HUMAN (26-635): 0: 911: 64.11