Interactor 1: RECK (O95980)
Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein)
Gene: RECK

Interactor 2: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 39499777, 21255571
Identification Methods proximity labelling technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0015026 - coreceptor activity
GO:0016020 - membrane
GO:0045765 - regulation of angiogenesis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 971
Hs

1 1255
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025