Interactor 1: IGF2 (P01344)
Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin]
Gene: IGF2
Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 1.00 | 0.852 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Insulin~fn3, Furin-like~Insulin, Insulin~Recep_L_domain |
| Common GO terms | GO:0005158 - insulin receptor binding GO:0008284 - positive regulation of cell population proliferation GO:0008286 - insulin receptor signaling pathway GO:0043410 - positive regulation of MAPK cascade GO:0048009 - insulin-like growth factor receptor signaling pathway and 1 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
