Interactor 1: TNFB (P01374)
Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)
Gene: LTA

Interactor 2: TNFB (P01374)
Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)
Gene: LTA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 23815148
Identification Methods blue native page
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNF
Common GO terms GO:0001666 - response to hypoxia
GO:0002876 - positive regulation of chronic inflammatory response to antigenic stimulus
GO:0002925 - positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
and 16 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 205
Hs

1 205
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024