Interactor 1: TNFB (P01374)
Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)
Gene: LTA
Interactor 2: TNFA (P01375)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: TNF
Species: Homo sapiens
Source: dip
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8171323 |
| Identification Methods | coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TNF~TNF |
| Common GO terms | GO:0001666 - response to hypoxia GO:0002876 - positive regulation of chronic inflammatory response to antigenic stimulus GO:0002925 - positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0005125 - cytokine activity GO:0005164 - tumor necrosis factor receptor binding and 8 others more... |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
