HitPredict

Interactor 1: IFNA2 (P01563)
Interferon alpha-2 (IFN-alpha-2) (Interferon alpha-A) (LeIF A)
Gene: IFNA2

Interactor 2: INAR1 (P17181)
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1)
Gene: IFNAR1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	1.00	0.719

Property	Details
Experiments	9334213, 7592797
Identification Methods	genetic interference, biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Interfer-bind~Interferon, Interferon~Tissue_fac
Common GO terms	GO:0060337 - type I interferon-mediated signaling pathway GO:0098586 - cellular response to virus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 557
+	Hs
		566005 IFNA8_HUMAN (1-188): 7.94e-95: 275: 82.01		INAR1_HUMAN (1-557): 1.37e-149: 442: 100.00
+	Hs
		352865 IFNB_HUMAN (1-186): 8.31e-49: 158: 32.98		INAR1_HUMAN (1-557): 1.37e-149: 442: 100.00
+	Hs
		352768 IFNA2_HUMAN (1-188): 1.27e-103: 297: 100.00		INAR2_HUMAN (37-202): 3.11e-09: 61.5: 16.57
+	Hs
		352827 IFNA5_HUMAN (1-188): 5.06e-103: 296: 83.60		INAR2_HUMAN (37-202): 3.11e-09: 61.5: 16.57
+	Hs
		352750 IFNA1_HUMAN (1-188): 3.15e-100: 288: 82.01		INAR2_HUMAN (37-202): 3.11e-09: 61.5: 16.57
+	Hs
		699608 IFNA8_HUMAN (1-188): 7.94e-95: 275: 82.01		INAR2_HUMAN (37-202): 3.11e-09: 61.5: 16.57
+	Hs
		392909 IFNW1_HUMAN (12-188): 1.67e-78: 234: 60.11		INAR2_HUMAN (37-202): 3.11e-09: 61.5: 16.57
+	Hs
		352874 IFNB_HUMAN (1-186): 8.31e-49: 158: 32.98		INAR2_HUMAN (37-202): 3.11e-09: 61.5: 16.57