HitPredict

Interactor 1: IFNA7 (P01567)
Interferon alpha-7 (IFN-alpha-7) (Interferon alpha-J) (LeIF J) (Interferon alpha-J1) (IFN-alpha-J1)
Gene: IFNA7

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19349300
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051607 - defense response to virus GO:0060337 - type I interferon-mediated signaling pathway GO:0098586 - cellular response to virus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 427
+	Hs
		352755 IFNA1_HUMAN (1-189): 4.37e-102: 293: 76.72		IRF3_HUMAN (1-427): 0: 604: 100.00
+	Hs
		352844 IFN14_HUMAN (1-189): 3.66e-101: 291: 80.95		IRF3_HUMAN (1-427): 0: 604: 100.00
+	Hs
		352770 IFNA2_HUMAN (1-189): 5.51e-96: 278: 77.78		IRF3_HUMAN (1-427): 0: 604: 100.00
+	Mm
		427402 IFNA4_MOUSE (1-189): 1.64e-82: 244: 53.68		IRF3_MOUSE (1-425): 0: 534: 71.06
+	Hs
		352753 IFNA1_HUMAN (1-189): 4.37e-102: 293: 76.72		IRF5_HUMAN (2-413): 1.48e-143: 420: 29.78
+	Hs
		352842 IFN14_HUMAN (1-189): 3.66e-101: 291: 80.95		IRF5_HUMAN (2-413): 1.48e-143: 420: 29.78
+	Mm
		427399 IFNA4_MOUSE (1-189): 1.64e-82: 244: 53.68		IRF8_MOUSE (7-393): 8.11e-150: 433: 28.04
+	Mm
		427400 IFNA4_MOUSE (1-189): 1.64e-82: 244: 53.68		IRF5_MOUSE (2-413): 1.06e-144: 423: 29.81
+	Mm
		427401 IFNA4_MOUSE (1-189): 1.64e-82: 244: 53.68		IRF7_MOUSE (2-383): 2.84e-131: 387: 27.92
+	Hs
		352758 IFNA1_HUMAN (1-189): 4.37e-102: 293: 76.72		IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03
+	Hs
		352791 IFNA7_HUMAN (1-189): 1.94e-101: 291: 100.00		IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03
+	Hs
		352848 IFN14_HUMAN (1-189): 3.66e-101: 291: 80.95		IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03
+	Hs
		352775 IFNA2_HUMAN (1-189): 5.51e-96: 278: 77.78		IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03
+	Hs
		352878 IFNB_HUMAN (1-186): 8.15e-51: 163: 31.55		IRF8_HUMAN (7-387): 6.94e-148: 428: 27.32
+	Hs
		352882 IFNB_HUMAN (1-186): 8.15e-51: 163: 31.55		IRF5_HUMAN (2-413): 1.48e-143: 420: 29.78
+	Hs
		352745 IFNA1_HUMAN (1-189): 4.37e-102: 293: 76.72		IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23
+	Hs
		352837 IFN14_HUMAN (1-189): 3.66e-101: 291: 80.95		IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23
+	Hs
		352766 IFNA2_HUMAN (1-189): 5.51e-96: 278: 77.78		IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23
+	Hs
		352861 IFNB_HUMAN (1-186): 8.15e-51: 163: 31.55		IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23
+	Hs
		352862 IFNB_HUMAN (1-186): 8.15e-51: 163: 31.55		IRF2_HUMAN (1-116): 1.85e-48: 170: 33.90