HitPredict

Interactor 1: IFN14 (P01570)
Interferon alpha-14 (IFN-alpha-14) (Interferon alpha-H) (LeIF H) (Interferon lambda-2-H)
Gene: IFNA14

Interactor 2: IRF5 (Q13568)
Interferon regulatory factor 5 (IRF-5)
Gene: IRF5

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	11303025
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019221 - cytokine-mediated signaling pathway GO:0051607 - defense response to virus GO:0098586 - cellular response to virus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 498
+	Hs
		352753 IFNA1_HUMAN (1-189): 1.37e-99: 287: 82.01		IRF5_HUMAN (1-498): 0: 628: 100.00
+	Mm
		427400 IFNA4_MOUSE (1-189): 5.7e-80: 237: 54.21		IRF5_MOUSE (1-498): 0: 602: 86.57
+	Hs
		352882 IFNB_HUMAN (8-186): 1.1e-56: 178: 30.94		IRF5_HUMAN (1-498): 0: 628: 100.00
+	Hs
		352755 IFNA1_HUMAN (1-189): 1.37e-99: 287: 82.01		IRF3_HUMAN (14-459): 1.3e-148: 433: 30.68
+	Hs
		352844 IFN14_HUMAN (1-189): 7.23e-99: 285: 100.00		IRF3_HUMAN (14-459): 1.3e-148: 433: 30.68
+	Hs
		352788 IFNA7_HUMAN (1-189): 7.88e-98: 283: 80.95		IRF3_HUMAN (14-459): 1.3e-148: 433: 30.68
+	Hs
		352770 IFNA2_HUMAN (1-189): 3.32e-93: 271: 82.01		IRF3_HUMAN (14-459): 1.3e-148: 433: 30.68
+	Mm
		427399 IFNA4_MOUSE (1-189): 5.7e-80: 237: 54.21		IRF8_MOUSE (16-454): 4.59e-145: 424: 32.59
+	Hs
		352758 IFNA1_HUMAN (1-189): 1.37e-99: 287: 82.01		IRF7_HUMAN (14-428): 1.73e-122: 369: 27.43
+	Hs
		352848 IFN14_HUMAN (1-189): 7.23e-99: 285: 100.00		IRF7_HUMAN (14-428): 1.73e-122: 369: 27.43
+	Hs
		352791 IFNA7_HUMAN (1-189): 7.88e-98: 283: 80.95		IRF7_HUMAN (14-428): 1.73e-122: 369: 27.43
+	Mm
		427402 IFNA4_MOUSE (1-189): 5.7e-80: 237: 54.21		IRF3_MOUSE (14-459): 1.65e-141: 415: 29.11
+	Hs
		352775 IFNA2_HUMAN (1-189): 3.32e-93: 271: 82.01		IRF7_HUMAN (14-428): 1.73e-122: 369: 27.43
+	Mm
		427401 IFNA4_MOUSE (1-189): 5.7e-80: 237: 54.21		IRF7_MOUSE (12-428): 2.61e-119: 359: 27.25
+	Hs
		352878 IFNB_HUMAN (8-186): 1.1e-56: 178: 30.94		IRF8_HUMAN (16-454): 1.66e-141: 415: 31.25
+	Hs
		352745 IFNA1_HUMAN (1-189): 1.37e-99: 287: 82.01		IRF1_HUMAN (11-233): 1.28e-51: 180: 24.56
+	Hs
		352837 IFN14_HUMAN (1-189): 7.23e-99: 285: 100.00		IRF1_HUMAN (11-233): 1.28e-51: 180: 24.56
+	Hs
		352766 IFNA2_HUMAN (1-189): 3.32e-93: 271: 82.01		IRF1_HUMAN (11-233): 1.28e-51: 180: 24.56
+	Hs
		352862 IFNB_HUMAN (8-186): 1.1e-56: 178: 30.94		IRF2_HUMAN (11-226): 3.14e-52: 182: 26.41
+	Hs
		352861 IFNB_HUMAN (8-186): 1.1e-56: 178: 30.94		IRF1_HUMAN (11-233): 1.28e-51: 180: 24.56