HitPredict

Interactor 1: IFNB (P01574)
Interferon beta (IFN-beta) (Fibroblast interferon)
Gene: IFNB1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	11090630, 19218087, 19349300
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 187 Hs			1 2442
+	Hs
		352757 IFNA1_HUMAN (10-186): 1.82e-74: 223: 31.49		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		352774 IFNA2_HUMAN (23-187): 2.08e-72: 218: 33.73		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		352790 IFNA7_HUMAN (9-186): 3.79e-72: 218: 32.62		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		352847 IFN14_HUMAN (10-186): 1.71e-71: 216: 32.60		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		352881 IFNB_HUMAN (1-187): 1.53e-76: 228: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		352752 IFNA1_HUMAN (10-186): 1.82e-74: 223: 31.49		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		352769 IFNA2_HUMAN (23-187): 2.08e-72: 218: 33.73		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		352787 IFNA7_HUMAN (9-186): 3.79e-72: 218: 32.62		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		352841 IFN14_HUMAN (10-186): 1.71e-71: 216: 32.60		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70882 IFNB_MOUSE (1-187): 4.49e-60: 186: 49.20		EP300_MOUSE (1-2426): 0: 867: 53.61