HitPredict

Interactor 1: IFNB (P01575)
Interferon beta (IFN-beta)
Gene: Ifnb1

Interactor 2: IRF7 (P70434)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19557165
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051607 - defense response to virus GO:0060337 - type I interferon-mediated signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 182 Mm			1 457
+	Mm
		427401 IFNA4_MOUSE (6-180): 7.74e-70: 211: 21.35		IRF7_MOUSE (1-457): 0: 525: 100.00
+	Hs
		352758 IFNA1_HUMAN (6-181): 3.79e-87: 255: 24.58		IRF7_HUMAN (1-455): 6.65e-152: 443: 62.08
+	Hs
		352775 IFNA2_HUMAN (13-182): 2.63e-86: 253: 26.74		IRF7_HUMAN (1-455): 6.65e-152: 443: 62.08
+	Hs
		352848 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF7_HUMAN (1-455): 6.65e-152: 443: 62.08
+	Hs
		352755 IFNA1_HUMAN (6-181): 3.79e-87: 255: 24.58		IRF3_HUMAN (6-453): 2.36e-151: 438: 28.38
+	Hs
		352791 IFNA7_HUMAN (6-181): 5.01e-85: 250: 24.58		IRF7_HUMAN (1-455): 6.65e-152: 443: 62.08
+	Hs
		352770 IFNA2_HUMAN (13-182): 2.63e-86: 253: 26.74		IRF3_HUMAN (6-453): 2.36e-151: 438: 28.38
+	Hs
		352844 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF3_HUMAN (6-453): 2.36e-151: 438: 28.38
+	Hs
		352788 IFNA7_HUMAN (6-181): 5.01e-85: 250: 24.58		IRF3_HUMAN (6-453): 2.36e-151: 438: 28.38
+	Hs
		352753 IFNA1_HUMAN (6-181): 3.79e-87: 255: 24.58		IRF5_HUMAN (8-449): 7.96e-127: 378: 26.61
+	Hs
		352842 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF5_HUMAN (8-449): 7.96e-127: 378: 26.61
+	Mm
		427402 IFNA4_MOUSE (6-180): 7.74e-70: 211: 21.35		IRF3_MOUSE (7-453): 8.49e-141: 411: 28.95
+	Mm
		427400 IFNA4_MOUSE (6-180): 7.74e-70: 211: 21.35		IRF5_MOUSE (8-440): 3.38e-133: 395: 26.59
+	Mm
		427399 IFNA4_MOUSE (6-180): 7.74e-70: 211: 21.35		IRF8_MOUSE (11-439): 1.91e-121: 362: 25.17
+	Hs
		352878 IFNB_HUMAN (1-182): 2.31e-66: 202: 49.20		IRF8_HUMAN (11-419): 4.41e-121: 361: 25.78
+	Hs
		352745 IFNA1_HUMAN (6-181): 3.79e-87: 255: 24.58		IRF1_HUMAN (7-234): 1.79e-34: 133: 21.89
+	Hs
		352766 IFNA2_HUMAN (13-182): 2.63e-86: 253: 26.74		IRF1_HUMAN (7-234): 1.79e-34: 133: 21.89
+	Hs
		352837 IFN14_HUMAN (6-181): 1.29e-85: 251: 27.37		IRF1_HUMAN (7-234): 1.79e-34: 133: 21.89
+	Hs
		352861 IFNB_HUMAN (1-182): 2.31e-66: 202: 49.20		IRF1_HUMAN (7-234): 1.79e-34: 133: 21.89
+	Hs
		352862 IFNB_HUMAN (1-182): 2.31e-66: 202: 49.20		IRF2_HUMAN (7-126): 2.12e-33: 130: 29.51