Interactor 1: IFNG (P01579)
Interferon gamma (IFN-gamma) (Immune interferon)
Gene: IFNG
Interactor 2: INGR1 (P15260)
Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)
Gene: IFNGR1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 10986460, 7673114, 33961781, 7617032, 10860730, 11250200 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, pull down, nuclear magnetic resonance, cross-linking study, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IFN-gamma~IFNGR1, IFN-gamma~Tissue_fac |
| Common GO terms | GO:0001774 - microglial cell activation GO:0009615 - response to virus GO:0010628 - positive regulation of gene expression GO:0032760 - positive regulation of tumor necrosis factor production GO:0038196 - type III interferon-mediated signaling pathway and 5 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
