Interactor 1: IFNG (P01579)
Interferon gamma (IFN-gamma) (Immune interferon)
Gene: IFNG

Interactor 2: INGR2 (P38484)
Interferon gamma receptor 2 (IFN-gamma receptor 2) (IFN-gamma-R2) (Interferon gamma receptor accessory factor 1) (AF-1) (Interferon gamma receptor beta-chain) (IFN-gamma-R-beta) (Interferon gamma transducer 1)
Gene: IFNGR2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 7673114
Identification Methods pull down, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IFN-gamma~Interfer-bind, IFN-gamma~Tissue_fac
Common GO terms GO:0001774 - microglial cell activation
GO:0007166 - cell surface receptor signaling pathway
GO:0009615 - response to virus
GO:0038196 - type III interferon-mediated signaling pathway
GO:0051607 - defense response to virus
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 166
Hs

1 337
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024