Interactor 1: IL1A (P01583)
Interleukin-1 alpha (IL-1 alpha) (Hematopoietin-1)
Gene: IL1A

Interactor 2: IL1R2 (P27930)
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]
Gene: IL1R2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 16971486, 1833184, 23395675
Identification Methods lambda repressor two hybrid, anti bait coimmunoprecipitation, competition binding, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IL1~ig
Common GO terms GO:0005576 - extracellular region
GO:0006955 - immune response
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 271
Hs

1 398
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024