Interactor 1: IL2RA (P01589)
Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25)
Gene: IL2RA

Interactor 2: IL2RB (P14784)
Interleukin-2 receptor subunit beta (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (Interleukin-15 receptor subunit beta) (p70-75) (p75) (CD antigen CD122)
Gene: IL2RB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 8006584, 1545122, 15178252, 8568232
Identification Methods biophysical, anti tag coimmunoprecipitation, isothermal titration calorimetry, protein cross-linking with a bifunctional reagent
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004911 - interleukin-2 receptor activity
GO:0005886 - plasma membrane
GO:0005893 - interleukin-2 receptor complex
GO:0009897 - external side of plasma membrane
GO:0019976 - interleukin-2 binding
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 272
Hs

1 551
+ Hs
+ Hs

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Last updated: 15 Jul 2024