Interactor 1: IL2RA (P01589)
Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25)
Gene: IL2RA

Interactor 2: IL2RG (P31785)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 8568232
Identification Methods protein cross-linking with a bifunctional reagent
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0009897 - external side of plasma membrane
GO:0019976 - interleukin-2 binding
GO:0038110 - interleukin-2-mediated signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 272
Hs

1 369
+ Hs
+ Hs

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Last updated: 15 Jul 2024