Interactor 1: IL2RA (P01590)
Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (p55) (CD antigen CD25)
Gene: IL2RA

Interactor 2: IL2 (P04351)
Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
Gene: IL2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 8894436, 8580082
Identification Methods competition binding, surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL2~Sushi
Common GO terms GO:0042102 - positive regulation of T cell proliferation
GO:0042104 - positive regulation of activated T cell proliferation
GO:0045582 - positive regulation of T cell differentiation
GO:0046013 - regulation of T cell homeostatic proliferation
GO:0046651 - lymphocyte proliferation
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 268
Mm

1 169
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024