HitPredict

Interactor 1: KV117 (P01599)
Immunoglobulin kappa variable 1-17 (Ig kappa chain V-I region Gal) (Ig kappa chain V-I region WEA)
Gene: IGKV1-17

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	29924966
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	ABC_membrane~V-set, ABC_tran~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 1480
+	Hs
		382257 KV311_HUMAN (3-117): 3.99e-45: 143: 62.61		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		353190 KV320_HUMAN (3-117): 1.38e-42: 137: 62.93		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528967 LV321_HUMAN (3-115): 4.11e-42: 136: 41.59		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		353207 LV140_HUMAN (3-115): 1.41e-41: 135: 46.55		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		353211 LV319_HUMAN (17-115): 2.1e-35: 119: 42.42		CFTR_HUMAN (1-1480): 0: 1031: 100.00