HitPredict

Interactor 1: LV208 (P01709)
Immunoglobulin lambda variable 2-8 (Ig lambda chain V-II region BO) (Ig lambda chain V-II region MGC)
Gene: IGLV2-8

Interactor 2: IGLC1 (P0CG04)
Immunoglobulin lambda constant 1 (Ig lambda chain C region MGC) (Ig lambda-1 chain C region)
Gene: IGLC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	2108322
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~V-set
Common GO terms	GO:0002250 - adaptive immune response GO:0003823 - antigen binding GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane and 1 others more... GO:0006955 - immune response
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 106
+	Hs
		353349 HV333_HUMAN (1-111): 7.95e-45: 143: 27.12		IGLC1_HUMAN (1-106): 4.95e-41: 132: 100.00
+	Mm
		526804 VPREB_MOUSE (1-117): 2.24e-40: 132: 38.21		IGLL1_MOUSE (1-106): 8.04e-38: 127: 67.93
+	Mm
		353201 KV3A8_MOUSE (20-116): 3.79e-41: 133: 44.44		GCAM_MOUSE (6-103): 7.95e-34: 122: 31.68
+	Mm
		353194 KV2A7_MOUSE (20-111): 1.67e-40: 131: 46.32		GCAM_MOUSE (6-103): 7.95e-34: 122: 31.68
+	Mm
		353195 KV2A7_MOUSE (20-111): 1.67e-40: 131: 46.32		IGG2B_MOUSE (6-103): 6.65e-32: 117: 30.69
+	Hs
		353698 Q8N355_HUMAN (1-118): 1.33e-47: 153: 53.39		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353180 KVD40_HUMAN (4-116): 5.26e-45: 143: 41.88		IGHM_HUMAN (7-93): 9.01e-10: 55.8: 36.26
+	Hs
		353350 HV307_HUMAN (1-111): 4.11e-44: 141: 25.42		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353208 LV208_HUMAN (1-118): 6.94e-44: 140: 100.00		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353347 HV323_HUMAN (1-111): 2.53e-43: 139: 27.97		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Hs
		353204 LV147_HUMAN (1-115): 6.76e-42: 135: 68.70		IGHM_HUMAN (7-93): 9.01e-10: 55.8: 36.26
+	Hs
		353203 LV147_HUMAN (1-115): 6.76e-42: 135: 68.70		IGHG1_HUMAN (7-104): 3.29e-09: 54.2: 24.04
+	Mm
		353202 KV3AD_MOUSE (20-116): 5.82e-42: 135: 44.44		IGHG1_MOUSE (4-105): 5.09e-09: 53.8: 26.92
+	Mm
		353221 LV1B_MOUSE (1-116): 1.26e-41: 135: 40.52		IGHG1_MOUSE (4-105): 5.09e-09: 53.8: 26.92
+	Mm
		353224 LV1E_MOUSE (1-116): 4.5e-41: 133: 38.79		IGHG1_MOUSE (4-105): 5.09e-09: 53.8: 26.92
+	Mm
		353196 KV2A7_MOUSE (20-111): 1.67e-40: 131: 46.32		IGHG1_MOUSE (4-105): 5.09e-09: 53.8: 26.92