HitPredict

Interactor 1: HV307 (P01780)
Immunoglobulin heavy variable 3-7 (Ig heavy chain V-III region GAL) (Ig heavy chain V-III region GAR) (Ig heavy chain V-III region JON)
Gene: IGHV3-7

Interactor 2: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	15174051
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~V-set
Common GO terms	GO:0003823 - antigen binding GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0070062 - extracellular exosome GO:0072562 - blood microparticle
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 399
+	Hs
		353347 HV323_HUMAN (1-117): 4.95e-55: 168: 86.33		IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00
+	Hs
		353698 Q8N355_HUMAN (1-116): 8e-38: 128: 24.14		IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00
+	Hs
		353750 HV431_HUMAN (1-117): 9.95e-42: 135: 46.22		IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48
+	Hs
		353871 HV431_HUMAN (1-117): 9.95e-42: 135: 46.22		IGHG4_HUMAN (1-399): 5.43e-99: 301: 91.98
+	Hs
		353208 LV208_HUMAN (1-116): 6.83e-32: 110: 26.50		IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00
+	Hs
		353837 HV431_HUMAN (1-117): 9.95e-42: 135: 46.22		IGHG3_HUMAN (1-399): 7.71e-97: 298: 83.86
+	Hs
		353203 LV147_HUMAN (7-116): 5.14e-25: 93: 26.36		IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00
+	Hs
		354141 Q9UL92_HUMAN (20-117): 7.51e-41: 133: 56.12		IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85
+	Hs
		353181 KVD40_HUMAN (4-117): 4e-38: 126: 21.85		IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85
+	Hs
		353205 LV147_HUMAN (7-116): 5.14e-25: 93: 26.36		IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85
+	Hs
		353349 HV333_HUMAN (1-117): 5.83e-57: 173: 87.18		IGLC1_HUMAN (2-103): 3.03e-11: 61.7: 31.43
+	Hs
		353180 KVD40_HUMAN (4-117): 4e-38: 126: 21.85		IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90
+	Mm
		526804 VPREB_MOUSE (1-116): 1.36e-40: 133: 29.06		IGLL1_MOUSE (2-103): 6.99e-12: 66.3: 30.48
+	Hs
		353204 LV147_HUMAN (7-116): 5.14e-25: 93: 26.36		IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90
+	Hs
		353209 LV208_HUMAN (1-116): 6.83e-32: 110: 26.50		IGLC1_HUMAN (2-103): 3.03e-11: 61.7: 31.43