HitPredict

Interactor 1: IGKC (P01837)
Immunoglobulin kappa constant (Ig kappa chain C region MOPC 21)
Gene: IGKC

Interactor 2: GCAB (P01864)
Ig gamma-2A chain C region secreted form (B allele)
Gene: GCAB

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.696

Property	Details
Experiments	8027997, 9413990
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 107 Mm			1 335
+	Hs
		353631 IGLL1_HUMAN (4-107): 3.79e-39: 131: 38.46		IGHG1_HUMAN (1-333): 2.12e-79: 249: 61.08
+	Hs
		353698 Q8N355_HUMAN (4-107): 1.54e-38: 130: 40.39		IGHG1_HUMAN (1-333): 2.12e-79: 249: 61.08
+	Hs
		353621 IGLC1_HUMAN (4-107): 7.27e-38: 124: 41.35		IGHG1_HUMAN (1-333): 2.12e-79: 249: 61.08
+	Hs
		354207 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		IGHD_HUMAN (1-332): 1.65e-49: 172: 21.43
+	Hs
		382387 HLAA_HUMAN (1-105): 1.49e-37: 131: 19.05		DRB3_HUMAN (173-332): 5.45e-34: 127: 21.51
+	Hs
		355008 HLAA_HUMAN (1-105): 1.49e-37: 131: 19.05		DQB1_HUMAN (188-332): 1.68e-33: 126: 22.93
+	Hs
		673951 HLAF_HUMAN (1-105): 2.65e-37: 130: 20.00		DRB3_HUMAN (173-332): 5.45e-34: 127: 21.51
+	Hs
		355019 HLAF_HUMAN (1-105): 2.65e-37: 130: 20.00		DQB1_HUMAN (188-332): 1.68e-33: 126: 22.93
+	Hs
		488189 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		DRB3_HUMAN (173-332): 5.45e-34: 127: 21.51
+	Hs
		355010 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		DQB1_HUMAN (188-332): 1.68e-33: 126: 22.93
+	Mm
		353580 IGHG1_MOUSE (5-103): 1.78e-36: 127: 29.00		LAC1_MOUSE (230-332): 6.24e-27: 104: 33.65
+	Hs
		354030 IGLC1_HUMAN (4-107): 7.27e-38: 124: 41.35		IGHA1_HUMAN (15-250): 3.36e-14: 74.6: 23.77
+	Hs
		82378 IGLL1_HUMAN (4-107): 3.79e-39: 131: 38.46		IGLL5_HUMAN (2-93): 2.11e-10: 61.8: 26.04
+	Hs
		82385 HLAF_HUMAN (1-105): 2.65e-37: 130: 20.00		IGLL5_HUMAN (2-93): 2.11e-10: 61.8: 26.04
+	Hs
		48911 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC7_HUMAN (2-93): 1.85e-10: 59.1: 29.17
+	Hs
		82374 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC6_HUMAN (2-93): 3.57e-10: 58.3: 27.08
+	Mm
		353576 IGHG1_MOUSE (5-103): 1.78e-36: 127: 29.00		IGKC_MOUSE (5-102): 2.96e-09: 56: 20.39