HitPredict

Interactor 1: IGKC (P01837)
Immunoglobulin kappa constant (Ig kappa chain C region MOPC 21)
Gene: IGKC

Interactor 2: IGG2B (P01867)
Immunoglobulin heavy constant gamma 2B (Ig gamma-2B chain C region)
Gene: Ighg2b

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	1749770, 8066444
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 107 Mm			1 404
+	Mm
		353574 IGKC_MOUSE (1-107): 9.51e-37: 121: 100.00		GCAM_MOUSE (1-404): 5.53e-114: 340: 78.47
+	Mm
		353577 IGKC_MOUSE (1-107): 9.51e-37: 121: 100.00		IGHG3_MOUSE (2-404): 2.22e-113: 338: 69.23
+	Mm
		353573 IGKC_MOUSE (1-107): 9.51e-37: 121: 100.00		GCAB_MOUSE (1-332): 6.7e-83: 258: 76.81
+	Mm
		353576 IGKC_MOUSE (1-107): 9.51e-37: 121: 100.00		IGHG1_MOUSE (1-334): 5.59e-82: 256: 62.87
+	Hs
		354207 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		IGHD_HUMAN (2-379): 6.28e-63: 210: 23.22
+	Hs
		354030 IGLC1_HUMAN (4-107): 7.27e-38: 124: 41.35		IGHA1_HUMAN (2-379): 5.15e-51: 177: 27.78
+	Hs
		588801 DPA1_HUMAN (2-106): 4.59e-35: 122: 21.91		KIRR1_HUMAN (3-380): 3.41e-25: 110: 13.65
+	Hs
		82378 IGLL1_HUMAN (4-107): 3.79e-39: 131: 38.46		IGLL5_HUMAN (5-101): 4.38e-10: 61: 26.73
+	Hs
		353631 IGLL1_HUMAN (4-107): 3.79e-39: 131: 38.46		IGHG1_HUMAN (1-131): 3.22e-09: 60.4: 25.37
+	Hs
		82385 HLAF_HUMAN (1-105): 2.65e-37: 130: 20.00		IGLL5_HUMAN (5-101): 4.38e-10: 61: 26.73
+	Hs
		353698 Q8N355_HUMAN (4-107): 1.54e-38: 130: 40.39		IGHG1_HUMAN (1-131): 3.22e-09: 60.4: 25.37
+	Hs
		48911 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC7_HUMAN (4-92): 6.19e-10: 57.9: 27.96
+	Hs
		82374 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC6_HUMAN (4-92): 1.84e-09: 56.7: 25.81
+	Hs
		82375 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC3_HUMAN (4-101): 2.44e-09: 56.3: 28.43
+	Hs
		353621 IGLC1_HUMAN (4-107): 7.27e-38: 124: 41.35		IGHG1_HUMAN (1-131): 3.22e-09: 60.4: 25.37
+	Mm
		353580 IGHG1_MOUSE (5-103): 1.78e-36: 127: 29.00		LAC1_MOUSE (3-93): 9.69e-09: 54.4: 23.16