HitPredict

Interactor 1: LAC1 (P01843)
Ig lambda-1 chain C region
Gene: LAC1

Interactor 2: IGHG1 (P01868)
Ig gamma-1 chain C region secreted form
Gene: IGHG1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	1713710, 11812141
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0003823 - antigen binding GO:0016064 - immunoglobulin mediated immune response
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 105 Mm			1 324
+	Hs
		353631 IGLL1_HUMAN (1-105): 1.5e-40: 134: 70.48		IGHG1_HUMAN (1-322): 2.36e-77: 243: 60.06
+	Hs
		353698 Q8N355_HUMAN (1-105): 9.79e-40: 133: 71.43		IGHG1_HUMAN (1-322): 2.36e-77: 243: 60.06
+	Hs
		353621 IGLC1_HUMAN (1-105): 1.52e-39: 128: 71.43		IGHG1_HUMAN (1-322): 2.36e-77: 243: 60.06
+	Hs
		353480 IGKC_HUMAN (4-104): 2.55e-35: 118: 38.46		IGHG1_HUMAN (1-322): 2.36e-77: 243: 60.06
+	Hs
		353481 IGKC_HUMAN (4-104): 2.55e-35: 118: 38.46		IGHG4_HUMAN (1-316): 7.74e-74: 234: 60.19
+	Hs
		353482 IGKC_HUMAN (4-104): 2.55e-35: 118: 38.46		IGHM_HUMAN (2-323): 1.64e-26: 110: 22.09
+	Hs
		570350 HLAG_HUMAN (1-99): 4.78e-36: 126: 23.23		CADM4_HUMAN (3-234): 5.85e-22: 96.9: 12.02
+	Hs
		354967 DRB1_HUMAN (1-105): 2.32e-36: 125: 25.00		CADM4_HUMAN (3-234): 5.85e-22: 96.9: 12.02
+	Hs
		354030 IGLC1_HUMAN (1-105): 1.52e-39: 128: 71.43		IGHA1_HUMAN (6-239): 3.84e-18: 86.1: 23.46
+	Hs
		354207 HLAC_HUMAN (1-100): 4.56e-37: 129: 25.00		IGHD_HUMAN (3-242): 1.99e-11: 66.5: 18.95
+	Hs
		82378 IGLL1_HUMAN (1-105): 1.5e-40: 134: 70.48		IGLL5_HUMAN (6-103): 5.34e-10: 60.2: 28.43
+	Hs
		82385 HLAF_HUMAN (1-99): 3.57e-38: 132: 24.24		IGLL5_HUMAN (6-103): 5.34e-10: 60.2: 28.43
+	Hs
		48911 IGLL5_HUMAN (1-105): 6.97e-40: 133: 71.43		IGLC7_HUMAN (5-103): 1.27e-09: 56.7: 30.10
+	Hs
		82374 IGLL5_HUMAN (1-105): 6.97e-40: 133: 71.43		IGLC6_HUMAN (5-103): 2.99e-09: 55.6: 28.16
+	Hs
		82375 IGLL5_HUMAN (1-105): 6.97e-40: 133: 71.43		IGLC3_HUMAN (5-103): 8.45e-09: 54.4: 30.10
+	Mm
		595692 IGLL1_MOUSE (1-105): 1.16e-37: 127: 70.48		IGLL1_MOUSE (4-103): 2.28e-09: 58.3: 26.92