Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: FCGR1 (P12314)
High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
Gene: FCGR1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 25925696
Identification Methods x-ray crystallography, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~ig, C1-set~Ig_2, C1-set~Ig_3
Common GO terms GO:0001788 - antibody-dependent cellular cytotoxicity
GO:0005886 - plasma membrane
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 399
Hs

1 374
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024