HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: IGLL1 (P15814)
Immunoglobulin lambda-like polypeptide 1 (CD179 antigen-like family member B) (Ig lambda-5) (Immunoglobulin omega polypeptide) (Immunoglobulin-related protein 14.1) (CD antigen CD179b)
Gene: IGLL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	15174051
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0003823 - antigen binding GO:0005576 - extracellular region GO:0071735 - IgG immunoglobulin complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 213
+	Hs
		353698 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		Q8N355_HUMAN (16-213): 1.01e-58: 186: 53.20
+	Hs
		353595 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGHG1_HUMAN (31-210): 2.89e-53: 177: 20.21
+	Hs
		353597 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGHG3_HUMAN (31-210): 5.31e-52: 175: 20.75
+	Hs
		353598 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGHG4_HUMAN (31-202): 2e-50: 170: 20.90
+	Hs
		353748 IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48		IGHG3_HUMAN (31-210): 5.31e-52: 175: 20.75
+	Hs
		353621 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGLC1_HUMAN (108-213): 2.21e-42: 140: 83.02
+	Hs
		353480 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGKC_HUMAN (109-212): 3.4e-37: 127: 36.45
+	Hs
		353481 IGHG4_HUMAN (1-399): 5.43e-99: 301: 91.98		IGKC_HUMAN (109-212): 3.4e-37: 127: 36.45
+	Mm
		353577 IGHG3_MOUSE (3-399): 7.23e-96: 293: 67.84		IGKC_MOUSE (109-212): 3.22e-38: 129: 37.38
+	Mm
		353575 IGG2B_MOUSE (2-399): 1.27e-94: 291: 63.95		IGKC_MOUSE (109-212): 3.22e-38: 129: 37.38
+	Mm
		353574 GCAM_MOUSE (2-399): 2.18e-94: 290: 66.92		IGKC_MOUSE (109-212): 3.22e-38: 129: 37.38
+	Hs
		353596 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		IGHG2_HUMAN (114-209): 1.26e-12: 67.6: 30.61
+	Mm
		353580 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		LAC1_MOUSE (109-213): 7.84e-42: 138: 70.48
+	Hs
		354030 IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85		IGLC1_HUMAN (108-213): 2.21e-42: 140: 83.02
+	Mm
		353576 IGHG1_MOUSE (1-329): 1.44e-67: 218: 60.79		IGKC_MOUSE (109-212): 3.22e-38: 129: 37.38
+	Mm
		353573 GCAB_MOUSE (1-327): 2.33e-63: 208: 61.26		IGKC_MOUSE (109-212): 3.22e-38: 129: 37.38