HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 245
+	Hs
		353760 IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		353658 IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		353911 IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		48912 IGLC7_HUMAN (2-103): 5.53e-12: 63.6: 33.33		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		647151 TITIN_HUMAN (7-349): 6.13e-09: 60.4: 9.88		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927352 TITIN_HUMAN (7-349): 6.13e-09: 60.4: 9.88		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		684121 Q6N089_HUMAN (17-336): 1.36e-15: 80.1: 16.90		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		684238 PALLD_HUMAN (43-358): 1.5e-10: 65.4: 11.39		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982332 PALLD_HUMAN (43-358): 1.5e-10: 65.4: 11.39		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43