Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: FCG2B (P31994)
Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)
Gene: FCGR2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 11567028
Identification Methods isothermal titration calorimetry, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~Ig_2
Common GO terms GO:0001788 - antibody-dependent cellular cytotoxicity
GO:0005886 - plasma membrane
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 399
Hs

1 310
+ Hs
+ Hs
+ Dr
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024