HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: FNDC5 (Q8NAU1)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Gene: FNDC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~fn3
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 212
+	Hs
		353797 IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48		FNDC5_HUMAN (1-212): 2.84e-147: 409: 100.00
+	Hs
		354096 IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85		FNDC5_HUMAN (1-212): 2.84e-147: 409: 100.00
+	Hs
		354175 IGHA2_HUMAN (1-374): 4.63e-60: 201: 28.72		FNDC5_HUMAN (1-212): 2.84e-147: 409: 100.00
+	Hs
		353972 IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90		FNDC5_HUMAN (1-212): 2.84e-147: 409: 100.00
+	Hs
		82432 IGLL5_HUMAN (2-103): 7.8e-12: 66.3: 31.43		FNDC5_HUMAN (1-212): 2.84e-147: 409: 100.00
+	Hs
		353541 IGKC_HUMAN (229-321): 1.52e-09: 57: 29.47		FNDC5_HUMAN (1-212): 2.84e-147: 409: 100.00