HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: EGFL8 (Q99944)
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)
Gene: EGFL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 293
+	Hs
		353810 IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		354122 IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		354071 IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85		FBLN7_HUMAN (63-186): 1.11e-15: 78.7: 23.12
+	Hs
		353987 IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		82452 IGLL5_HUMAN (2-103): 7.8e-12: 66.3: 31.43		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		48917 IGLC7_HUMAN (2-103): 5.53e-12: 63.6: 33.33		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		353555 IGKC_HUMAN (229-321): 1.52e-09: 57: 29.47		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		1268526 PXDN_HUMAN (2-154): 1.82e-11: 68.1: 12.26		NELL1_HUMAN (110-186): 2.35e-23: 101: 34.94
+	Hs
		1268531 PXDN_HUMAN (2-154): 1.82e-11: 68.1: 12.26		NELL2_HUMAN (95-186): 1.8e-19: 90.2: 29.59
+	Hs
		550306 IGLL1_HUMAN (2-103): 1.05e-11: 65.9: 31.43		FAT1_HUMAN (7-64): 2.74e-13: 72.1: 10.35
+	Hs
		980481 PXDN_HUMAN (2-154): 1.82e-11: 68.1: 12.26		NOTC2_HUMAN (4-199): 2.38e-12: 69.4: 11.49
+	Hs
		296682 ROBO1_HUMAN (207-358): 4.52e-11: 67: 11.80		SLIT2_HUMAN (71-179): 1.2e-09: 60.9: 16.38
+	Mm
		292557 ROBO1_MOUSE (206-358): 3.88e-11: 67: 11.11		SLIT3_MOUSE (3-108): 1.83e-09: 60.5: 11.32
+	Dr
		65450 A8DZ85_DANRE (215-358): 5.56e-11: 66.6: 11.77		Q3Y6S4_DANRE (71-179): 9.93e-09: 58.2: 17.65