HitPredict

Interactor 1: IGHG2 (P01859)
Immunoglobulin heavy constant gamma 2 (Ig gamma-2 chain C region) (Ig gamma-2 chain C region DOT) (Ig gamma-2 chain C region TIL) (Ig gamma-2 chain C region ZIE)
Gene: IGHG2

Interactor 2: AL3A1 (P30838)
Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDHIII) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1)
Gene: ALDH3A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 395 Hs			1 453
+	Hs
		353611 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353641 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		AL3A1_HUMAN (1-453): 0: 522: 100.00
+	Hs
		353869 IGHG4_HUMAN (1-395): 5.15e-105: 317: 93.18		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353836 IGHG3_HUMAN (1-395): 6.18e-101: 308: 82.06		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353844 IGHG3_HUMAN (1-395): 6.18e-101: 308: 82.06		AL3A1_HUMAN (1-453): 0: 522: 100.00
+	Hs
		354025 IGHA1_HUMAN (1-370): 2.19e-65: 215: 29.52		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		676674 MYLK_HUMAN (5-103): 1.6e-09: 62: 11.11		AL1B1_HUMAN (2-431): 0: 532: 27.25
+	Hs
		82386 IGLL5_HUMAN (6-104): 3.11e-11: 64.4: 31.37		AL3A1_HUMAN (1-453): 0: 522: 100.00
+	Hs
		396472 MYLK_HUMAN (5-103): 1.6e-09: 62: 11.11		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353487 IGKC_HUMAN (225-317): 5.2e-10: 58.2: 29.47		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353497 IGKC_HUMAN (225-317): 5.2e-10: 58.2: 29.47		AL3A1_HUMAN (1-453): 0: 522: 100.00