HitPredict

Interactor 1: IGHG2 (P01859)
Immunoglobulin heavy constant gamma 2 (Ig gamma-2 chain C region) (Ig gamma-2 chain C region DOT) (Ig gamma-2 chain C region TIL) (Ig gamma-2 chain C region ZIE)
Gene: IGHG2

Interactor 2: FNDC1 (Q4ZHG4)
Fibronectin type III domain-containing protein 1 (Activation-associated cDNA protein) (Expressed in synovial lining protein)
Gene: FNDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~fn3
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 395 Hs			1 1894
+	Hs
		353676 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		FNDC1_HUMAN (1-1894): 0: 684: 100.00
+	Hs
		82419 IGLL5_HUMAN (6-104): 3.11e-11: 64.4: 31.37		FNDC1_HUMAN (1-1894): 0: 684: 100.00
+	Hs
		353522 IGKC_HUMAN (225-317): 5.2e-10: 58.2: 29.47		FNDC1_HUMAN (1-1894): 0: 684: 100.00
+	Hs
		353604 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		FINC_HUMAN (339-1757): 1.12e-11: 72.8: 9.51
+	Hs
		353707 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		TITIN_HUMAN (1618-1808): 8.9e-10: 66.7: 16.92
+	Dm
		333143 Q9VMN6_DROME (6-345): 1.49e-49: 178: 12.17		SDK_DROME (39-460): 2.83e-24: 114: 19.73
+	Hs
		354020 IGHA1_HUMAN (1-370): 2.19e-65: 215: 29.52		FINC_HUMAN (339-1757): 1.12e-11: 72.8: 9.51
+	Dm
		53783 Q9W213_DROME (1-379): 1.8e-44: 167: 11.55		A1Z920_DROME (1026-1758): 3.31e-17: 90.5: 10.71
+	Hs
		1264775 TITIN_HUMAN (1-107): 2.98e-10: 64.7: 14.95		NEO1_HUMAN (1150-1755): 3.59e-32: 139: 11.88
+	Hs
		616939 PTPRD_HUMAN (115-391): 6.43e-27: 115: 13.68		PTPRD_HUMAN (1541-1826): 1.57e-16: 88.6: 14.93
+	Hs
		82439 IGLL5_HUMAN (6-104): 3.11e-11: 64.4: 31.37		NEO1_HUMAN (1150-1755): 3.59e-32: 139: 11.88
+	Hs
		616971 PTPRD_HUMAN (115-391): 6.43e-27: 115: 13.68		PTPRS_HUMAN (1658-1811): 8.66e-11: 69.7: 18.83
+	Hs
		353903 IGHM_HUMAN (1-383): 3.57e-24: 105: 20.75		FINC_HUMAN (339-1757): 1.12e-11: 72.8: 9.51
+	Hs
		489957 PTPRF_HUMAN (2-337): 2.73e-17: 86.2: 11.91		PTPRS_HUMAN (1658-1811): 8.66e-11: 69.7: 18.83
+	Ce
		136802 UNC89_CAEEL (3-170): 6.36e-11: 66.6: 14.04		UNC22_CAEEL (8-197): 4.35e-15: 84: 15.46
+	Hs
		489886 PTPRF_HUMAN (2-337): 2.73e-17: 86.2: 11.91		PTPRF_HUMAN (1168-1749): 6.16e-09: 63.4: 10.77
+	Hs
		870000 TITIN_HUMAN (1-107): 2.98e-10: 64.7: 14.95		MYOM2_HUMAN (1618-1795): 2.85e-15: 84.4: 16.58
+	Hs
		363240 TITIN_HUMAN (1-107): 2.98e-10: 64.7: 14.95		FINC_HUMAN (339-1757): 1.12e-11: 72.8: 9.51
+	Hs
		82367 IGLL5_HUMAN (6-104): 3.11e-11: 64.4: 31.37		FINC_HUMAN (339-1757): 1.12e-11: 72.8: 9.51
+	Hs
		1264771 TITIN_HUMAN (1-107): 2.98e-10: 64.7: 14.95		TITIN_HUMAN (1618-1808): 8.9e-10: 66.7: 16.92