HitPredict

Interactor 1: IGHG2 (P01859)
Immunoglobulin heavy constant gamma 2 (Ig gamma-2 chain C region) (Ig gamma-2 chain C region DOT) (Ig gamma-2 chain C region TIL) (Ig gamma-2 chain C region ZIE)
Gene: IGHG2

Interactor 2: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 395 Hs			1 321
+	Hs
		353680 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		353883 IGHG4_HUMAN (1-395): 5.15e-105: 317: 93.18		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		353850 IGHG3_HUMAN (1-395): 6.18e-101: 308: 82.06		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		354075 IGHA1_HUMAN (1-370): 2.19e-65: 215: 29.52		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		353947 IGHM_HUMAN (1-383): 3.57e-24: 105: 20.75		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		82421 IGLL5_HUMAN (6-104): 3.11e-11: 64.4: 31.37		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		474415 IGLC6_HUMAN (5-104): 7.15e-11: 60.5: 31.07		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		353527 IGKC_HUMAN (225-317): 5.2e-10: 58.2: 29.47		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		851873 ROBO3_HUMAN (5-381): 1.62e-23: 105: 11.63		UB2E1_HUMAN (3-153): 1.32e-66: 209: 25.17
+	Hs
		829039 TITIN_HUMAN (1-107): 2.98e-10: 64.7: 14.95		UBE2A_HUMAN (1-151): 5.75e-68: 210: 33.11