HitPredict

Interactor 1: IGHG2 (P01859)
Immunoglobulin heavy constant gamma 2 (Ig gamma-2 chain C region) (Ig gamma-2 chain C region DOT) (Ig gamma-2 chain C region TIL) (Ig gamma-2 chain C region ZIE)
Gene: IGHG2

Interactor 2: CERS3 (Q8IU89)
Ceramide synthase 3 (CerS3) (Dihydroceramide synthase 3) (LAG1 longevity assurance homolog 3) (Sphingosine N-acyltransferase CERS3) (EC 2.3.1.24) (Ultra-long-chain ceramide synthase CERS3) (EC 2.3.1.298) (Very-long-chain ceramide synthase CERS3) (EC 2.3.1.297)
Gene: CERS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 395 Hs			1 383
+	Hs
		353694 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		353885 IGHG4_HUMAN (1-395): 5.15e-105: 317: 93.18		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		353853 IGHG3_HUMAN (1-395): 6.18e-101: 308: 82.06		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		353965 IGHM_HUMAN (1-383): 3.57e-24: 105: 20.75		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		48914 IGLC7_HUMAN (5-104): 5.61e-11: 60.9: 32.04		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00
+	Hs
		353536 IGKC_HUMAN (225-317): 5.2e-10: 58.2: 29.47		CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00