HitPredict

Interactor 1: IGHG2 (P01859)
Immunoglobulin heavy constant gamma 2 (Ig gamma-2 chain C region) (Ig gamma-2 chain C region DOT) (Ig gamma-2 chain C region TIL) (Ig gamma-2 chain C region ZIE)
Gene: IGHG2

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.504

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 395 Hs			1 541
+	Hs
		353718 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353894 IGHG4_HUMAN (1-395): 5.15e-105: 317: 93.18		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353861 IGHG3_HUMAN (1-395): 6.18e-101: 308: 82.06		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		354118 IGHA1_HUMAN (1-370): 2.19e-65: 215: 29.52		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		354186 IGHA2_HUMAN (1-370): 4.91e-64: 211: 27.74		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353982 IGHM_HUMAN (1-383): 3.57e-24: 105: 20.75		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		82446 IGLL5_HUMAN (6-104): 3.11e-11: 64.4: 31.37		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353727 IGHG1_HUMAN (1-395): 9.55e-111: 331: 90.23		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Mm
		956929 SHPS1_MOUSE (1-334): 8.52e-54: 187: 18.80		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		990914 KIRR1_HUMAN (4-309): 1.57e-15: 80.4: 13.64		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97