HitPredict

Interactor 1: IGHG3 (P01860)
Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region)
Gene: IGHG3

Interactor 2: AL3A1 (P30838)
Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDHIII) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1)
Gene: ALDH3A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 453
+	Hs
		353836 IGHG3_HUMAN (1-446): 1.6e-145: 424: 100.00		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353611 IGHG1_HUMAN (1-446): 6.57e-137: 400: 84.53		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353641 IGHG1_HUMAN (1-446): 6.57e-137: 400: 84.53		AL3A1_HUMAN (1-453): 0: 522: 100.00
+	Hs
		353761 IGHG2_HUMAN (1-446): 1.51e-131: 386: 78.25		AL3A1_HUMAN (1-453): 0: 522: 100.00
+	Hs
		353869 IGHG4_HUMAN (1-446): 1.07e-128: 379: 82.29		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		354025 IGHA1_HUMAN (1-421): 7.69e-52: 181: 27.69		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		82386 IGLL5_HUMAN (263-372): 1.79e-32: 124: 31.25		AL3A1_HUMAN (1-453): 0: 522: 100.00
+	Hs
		353487 IGKC_HUMAN (276-368): 1.51e-09: 57: 28.42		ALDH2_HUMAN (3-431): 0: 524: 26.86
+	Hs
		353497 IGKC_HUMAN (276-368): 1.51e-09: 57: 28.42		AL3A1_HUMAN (1-453): 0: 522: 100.00