HitPredict

Interactor 1: IGHG3 (P01860)
Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region)
Gene: IGHG3

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 581
+	Hs
		353725 IGHG1_HUMAN (1-446): 6.57e-137: 400: 84.53		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		353813 IGHG2_HUMAN (1-446): 1.51e-131: 386: 78.25		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		353897 IGHG4_HUMAN (1-446): 1.07e-128: 379: 82.29		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		354124 IGHA1_HUMAN (1-421): 7.69e-52: 181: 27.69		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		82454 IGLL5_HUMAN (263-372): 1.79e-32: 124: 31.25		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		681784 SHPS1_HUMAN (34-403): 2.25e-52: 185: 15.50		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		353557 IGKC_HUMAN (276-368): 1.51e-09: 57: 28.42		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00