HitPredict

Interactor 1: IGHM (P01871)
Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU)
Gene: IGHM

Interactor 2: EGFL8 (Q99944)
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)
Gene: EGFL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009986 - cell surface
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 293
+	Dm
		621591 Q9GPP6_DROME (9-470): 1.75e-59: 213: 14.16		SLIT_DROME (103-290): 2.75e-24: 104: 15.42
+	Dm
		621595 Q9VPZ7_DROME (9-470): 1.64e-59: 213: 14.16		SLIT_DROME (103-290): 2.75e-24: 104: 15.42
+	Hs
		354122 IGHA1_HUMAN (21-242): 4.43e-18: 88.1: 23.01		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		353723 IGHG1_HUMAN (5-220): 4.48e-16: 82: 15.98		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		353810 IGHG2_HUMAN (7-220): 4.43e-15: 78.9: 15.21		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		82452 IGLL5_HUMAN (96-213): 3.75e-13: 70.2: 22.88		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Hs
		48917 IGLC7_HUMAN (107-212): 2.2e-12: 65.2: 25.47		EGFL8_HUMAN (1-293): 6.97e-41: 145: 100.00
+	Mm
		292557 ROBO1_MOUSE (2-400): 6.18e-34: 138: 13.90		SLIT3_MOUSE (3-108): 1.83e-09: 60.5: 11.32
+	Hs
		296682 ROBO1_HUMAN (2-400): 2.86e-33: 135: 12.65		SLIT2_HUMAN (71-179): 1.2e-09: 60.9: 16.38
+	Hs
		1268526 PXDN_HUMAN (2-108): 7.22e-13: 73.2: 14.02		NELL1_HUMAN (110-186): 2.35e-23: 101: 34.94
+	Dm
		219803 O44924_DROME (323-472): 2.22e-11: 68.5: 14.00		SLIT_DROME (103-290): 2.75e-24: 104: 15.42
+	Dm
		621597 Q9W213_DROME (323-472): 2.17e-11: 68.5: 14.00		SLIT_DROME (103-290): 2.75e-24: 104: 15.42
+	Hs
		354071 IGHA1_HUMAN (21-242): 4.43e-18: 88.1: 23.01		FBLN7_HUMAN (63-186): 1.11e-15: 78.7: 23.12
+	Hs
		1268531 PXDN_HUMAN (2-108): 7.22e-13: 73.2: 14.02		NELL2_HUMAN (95-186): 1.8e-19: 90.2: 29.59
+	Hs
		1298001 ROBO3_HUMAN (305-472): 1.82e-11: 68.9: 11.18		NELL2_HUMAN (95-186): 1.8e-19: 90.2: 29.59
+	Hs
		980481 PXDN_HUMAN (2-108): 7.22e-13: 73.2: 14.02		NOTC2_HUMAN (4-199): 2.38e-12: 69.4: 11.49
+	Hs
		550306 IGLL1_HUMAN (107-212): 6.47e-12: 66.8: 22.64		FAT1_HUMAN (7-64): 2.74e-13: 72.1: 10.35
+	Dr
		65450 A8DZ85_DANRE (6-287): 4.4e-12: 70.9: 11.11		Q3Y6S4_DANRE (71-179): 9.93e-09: 58.2: 17.65