HitPredict

Interactor 1: IGHA1 (P01876)
Immunoglobulin heavy constant alpha 1 (Ig alpha-1 chain C region) (Ig alpha-1 chain C region BUR) (Ig alpha-1 chain C region TRO)
Gene: IGHA1

Interactor 2: CCR1 (P32246)
C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (HM145) (LD78 receptor) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)
Gene: CCR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006955 - immune response
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 398 Hs			1 355
+	Hs
		353643 IGHG1_HUMAN (1-392): 3.96e-74: 238: 29.07		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		353762 IGHG2_HUMAN (1-392): 4.13e-72: 232: 29.40		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		354146 IGHA2_HUMAN (1-398): 8.81e-71: 229: 88.37		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		353875 IGHG4_HUMAN (1-392): 1.93e-68: 223: 29.40		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		353845 IGHG3_HUMAN (1-392): 1.55e-66: 219: 25.90		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		354210 IGHD_HUMAN (1-387): 3.89e-64: 212: 25.17		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		127657 IGHA1_HUMAN (1-398): 4.69e-77: 245: 100.00		CCRL2_HUMAN (4-319): 5.77e-77: 241: 43.30
+	Hs
		353645 IGHG1_HUMAN (1-392): 3.96e-74: 238: 29.07		ADA1B_HUMAN (1-320): 5.62e-68: 223: 17.47
+	Hs
		353912 IGHM_HUMAN (2-370): 4.97e-21: 96.6: 18.49		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00
+	Hs
		353498 IGKC_HUMAN (225-327): 1.76e-12: 65.2: 23.30		CCR1_HUMAN (1-355): 4.53e-90: 276: 100.00