HitPredict

Interactor 1: IGHA2 (P01877)
Immunoglobulin heavy constant alpha 2 (Ig alpha-2 chain C region) (Ig alpha-2 chain C region BUT) (Ig alpha-2 chain C region LAN)
Gene: IGHA2

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.504

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 541
+	Hs
		354118 IGHA1_HUMAN (1-391): 1.69e-70: 228: 89.11		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353806 IGHG2_HUMAN (1-385): 1.11e-67: 221: 27.46		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353718 IGHG1_HUMAN (1-385): 8.57e-67: 218: 25.69		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353894 IGHG4_HUMAN (1-385): 6.65e-63: 208: 26.63		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353861 IGHG3_HUMAN (1-385): 1.54e-60: 203: 24.11		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353982 IGHM_HUMAN (128-389): 4.79e-16: 81.3: 17.29		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		82446 IGLL5_HUMAN (211-306): 3.88e-11: 64.1: 33.33		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		353727 IGHG1_HUMAN (1-385): 8.57e-67: 218: 25.69		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Mm
		956929 SHPS1_MOUSE (9-333): 4.73e-61: 207: 16.86		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Mm
		530209 NCAM1_MOUSE (11-362): 1.02e-40: 155: 13.48		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Hs
		990914 KIRR1_HUMAN (3-320): 2.73e-27: 115: 13.17		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97