HitPredict

Interactor 1: B2MG (P01887)
Beta-2-microglobulin
Gene: B2m

Interactor 2: HA1L (P01897)
H-2 class I histocompatibility antigen, L-D alpha chain
Gene: H2-L

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9620676
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set, C1-set~MHC_I
Common GO terms	GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0005615 - extracellular space GO:0009897 - external side of plasma membrane GO:0030670 - phagocytic vesicle membrane GO:0042605 - peptide antigen binding and 1 others more... GO:0042612 - MHC class I protein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 119 Mm			1 362
+	Hs
		382258 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAA_HUMAN (1-361): 1.33e-171: 483: 67.58
+	Hs
		354627 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAH_HUMAN (1-359): 2.33e-156: 445: 67.13
+	Hs
		382467 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		Q860B5_HUMAN (26-337): 2.26e-154: 437: 67.95
+	Hs
		354248 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAB_HUMAN (1-359): 1.4e-151: 432: 68.51
+	Hs
		354258 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAB_HUMAN (1-359): 1.4e-151: 432: 68.51
+	Hs
		354240 HLAH_HUMAN (7-117): 1.23e-42: 144: 21.93		HLAB_HUMAN (1-359): 1.4e-151: 432: 68.51
+	Hs
		382299 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAG_HUMAN (1-338): 8.75e-150: 427: 65.09
+	Hs
		488119 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAG_HUMAN (1-338): 8.75e-150: 427: 65.09
+	Hs
		382277 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAC_HUMAN (1-362): 9.37e-147: 421: 66.94
+	Hs
		488101 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAC_HUMAN (1-362): 9.37e-147: 421: 66.94
+	Hs
		382286 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAE_HUMAN (20-356): 1.56e-142: 409: 64.69
+	Hs
		488112 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAE_HUMAN (20-356): 1.56e-142: 409: 64.69
+	Hs
		382321 HLAA_HUMAN (2-116): 6.78e-44: 148: 20.34		HLAF_HUMAN (4-348): 8.83e-142: 407: 64.35
+	Hs
		488136 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HLAF_HUMAN (4-348): 8.83e-142: 407: 64.35
+	Hs
		354630 HLAH_HUMAN (7-117): 1.23e-42: 144: 21.93		HLAE_HUMAN (20-356): 1.56e-142: 409: 64.69
+	Hs
		488259 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		Q6F3D7_HUMAN (26-298): 1.52e-134: 386: 74.73
+	Hs
		488329 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		HMR1_HUMAN (1-349): 2.93e-115: 340: 37.61
+	Hs
		488390 HLAC_HUMAN (2-117): 1.4e-43: 147: 20.17		Q9MY50_HUMAN (1-206): 1.03e-95: 285: 68.93