HitPredict

Interactor 1: HLAB (P01889)
HLA class I histocompatibility antigen, B alpha chain (Human leukocyte antigen B) (HLA-B)
Gene: HLA-B

Interactor 2: KLRD1 (Q13241)
Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
Gene: KLRD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms	GO:0002250 - adaptive immune response GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 362 Hs			1 179
+	Hs
		382490 HLAA_HUMAN (1-362): 1.12e-170: 481: 85.64		CLC4D_HUMAN (2-175): 1.43e-42: 143: 19.15
+	Hs
		382561 HLAA_HUMAN (1-362): 1.12e-170: 481: 85.64		CLC4A_HUMAN (16-179): 3.06e-41: 140: 22.29
+	Hs
		382559 HLAA_HUMAN (1-362): 1.12e-170: 481: 85.64		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		382491 HLAA_HUMAN (1-362): 1.12e-170: 481: 85.64		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		354602 HLAB_HUMAN (1-362): 1.76e-154: 440: 100.00		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		354302 HLAB_HUMAN (1-362): 1.76e-154: 440: 100.00		NKG2A_HUMAN (10-178): 1.25e-36: 128: 31.95
+	Hs
		488205 HLAC_HUMAN (1-361): 4.61e-145: 416: 85.08		KLRD1_HUMAN (1-179): 2.95e-46: 151: 100.00
+	Hs
		488317 HLAC_HUMAN (1-361): 4.61e-145: 416: 85.08		CLC4D_HUMAN (2-175): 1.43e-42: 143: 19.15
+	Hs
		533144 HLAE_HUMAN (20-357): 3.41e-141: 406: 77.81		KLRD1_HUMAN (1-179): 2.95e-46: 151: 100.00
+	Hs
		488421 HLAC_HUMAN (1-361): 4.61e-145: 416: 85.08		CLC4A_HUMAN (16-179): 3.06e-41: 140: 22.29
+	Hs
		488420 HLAC_HUMAN (1-361): 4.61e-145: 416: 85.08		CLC4E_HUMAN (1-176): 8.25e-41: 138: 17.02
+	Hs
		570305 HLAG_HUMAN (1-338): 2.56e-148: 423: 80.77		NKG2A_HUMAN (10-178): 1.25e-36: 128: 31.95
+	Hs
		488269 HLAC_HUMAN (1-361): 4.61e-145: 416: 85.08		CLC4G_HUMAN (2-177): 1.85e-38: 134: 21.62
+	Hs
		533125 HLAE_HUMAN (20-357): 3.41e-141: 406: 77.81		NKG2C_HUMAN (10-178): 2.93e-39: 135: 30.18
+	Hs
		488322 HLAC_HUMAN (1-361): 4.61e-145: 416: 85.08		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		533124 HLAE_HUMAN (20-357): 3.41e-141: 406: 77.81		NKG2A_HUMAN (10-178): 1.25e-36: 128: 31.95
+	Hs
		673960 HLAF_HUMAN (4-348): 9.26e-138: 397: 79.71		CL12B_HUMAN (53-176): 6.44e-39: 135: 32.06
+	Hs
		533155 HLAE_HUMAN (20-357): 3.41e-141: 406: 77.81		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		673971 HLAF_HUMAN (4-348): 9.26e-138: 397: 79.71		CLC2B_HUMAN (50-178): 1.36e-34: 120: 26.72
+	Hs
		570381 HLAG_HUMAN (1-338): 2.56e-148: 423: 80.77		MRC2_HUMAN (73-174): 1.04e-14: 73.1: 19.63