HitPredict

Interactor 1: DRA (P01903)
HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)
Gene: HLA-DRA

Interactor 2: DQA1 (P01909)
HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain) (DC-alpha) (HLA-DCA) (MHC class II DQA1)
Gene: HLA-DQA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_II_alpha, MHC_II_alpha~MHC_II_alpha
Common GO terms GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
and 15 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 254
Hs

1 254
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024