HitPredict

Interactor 1: DQB1 (P01920)
HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1)
Gene: HLA-DQB1

Interactor 2: ASIC4 (Q96FT7)
Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary)
Gene: ASIC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 539
+	Hs
		382497 HLAA_HUMAN (3-257): 2.1e-100: 298: 22.22		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		945213 DRB3_HUMAN (7-258): 3.66e-95: 281: 61.51		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		354532 HLAB_HUMAN (3-237): 1.18e-91: 276: 21.76		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		488337 HLAC_HUMAN (3-233): 3.8e-90: 272: 20.43		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		354978 DRB1_HUMAN (7-258): 3.18e-90: 269: 63.10		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		942290 DRB3_HUMAN (7-258): 3.66e-95: 281: 61.51		ASIC1_HUMAN (36-539): 0: 536: 48.95
+	Hs
		488188 HLAC_HUMAN (3-233): 3.8e-90: 272: 20.43		ASIC1_HUMAN (36-539): 0: 536: 48.95
+	Hs
		570317 HLAG_HUMAN (23-242): 2.95e-86: 261: 24.11		ASIC1_HUMAN (36-539): 0: 536: 48.95
+	Hs
		1103656 HFE_HUMAN (61-240): 7.19e-16: 77.8: 29.73		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		1278662 HMR1_HUMAN (61-257): 1.08e-14: 74.3: 25.50		ASIC4_HUMAN (1-539): 0: 580: 100.00
+	Hs
		382357 HLAA_HUMAN (3-257): 2.1e-100: 298: 22.22		SCNND_HUMAN (26-529): 1.36e-112: 354: 23.71
+	Hs
		382585 DPB1_HUMAN (5-257): 2.47e-92: 274: 62.45		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00
+	Hs
		354933 DRB1_HUMAN (7-258): 3.18e-90: 269: 63.10		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00
+	Hs
		570308 HLAG_HUMAN (23-242): 2.95e-86: 261: 24.11		SCNNA_HUMAN (5-156): 2.5e-30: 127: 20.00