HitPredict

Interactor 1: H2B (P02283)
Histone H2B
Gene: H2B, His2B;

Interactor 2: H2AV (P08985)
Histone H2A.v (H2A.F/Z) (H2A.Z)
Gene: His2Av

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.744

Property	Details
Experiments	27956707, 20347990
Identification Methods	protein complementation assay, biochemical
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0044877 - protein-containing complex binding GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 123 Dm			1 141
+	Hs
		1151403 U3KQK0_HUMAN (3-123): 2.56e-50: 158: 81.30		H2A2A_HUMAN (5-132): 1.71e-59: 181: 61.24
+	Hs
		391992 U3KQK0_HUMAN (3-123): 2.56e-50: 158: 81.30		H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47
+	Hs
		555619 H2B1M_HUMAN (3-123): 2.3e-49: 155: 80.49		H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04
+	Hs
		555295 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04
+	Hs
		555496 H2B2F_HUMAN (3-123): 3.44e-49: 154: 81.30		H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04
+	Hs
		1307102 H2B1M_HUMAN (3-123): 2.3e-49: 155: 80.49		H2A1J_HUMAN (5-130): 2.43e-59: 181: 60.63
+	Hs
		391868 H2B1M_HUMAN (3-123): 2.3e-49: 155: 80.49		H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47
+	Hs
		391552 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47
+	Hs
		391736 H2B2F_HUMAN (3-123): 3.44e-49: 154: 81.30		H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47
+	Hs
		391831 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47
+	Hs
		469948 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36
+	Hs
		470046 H2B2F_HUMAN (3-123): 3.44e-49: 154: 81.30		H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36
+	Hs
		470118 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36
+	Hs
		470271 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47
+	Hs
		470411 H2B2F_HUMAN (3-123): 3.44e-49: 154: 81.30		H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47
+	Hs
		594822 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2A1D_HUMAN (5-132): 2.65e-59: 181: 61.24
+	Hs
		617952 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2A2A_HUMAN (5-132): 1.71e-59: 181: 61.24
+	Hs
		1129818 H2B2F_HUMAN (3-123): 3.44e-49: 154: 81.30		H2AV_HUMAN (1-122): 6.81e-59: 180: 98.36
+	Hs
		617950 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2A2C_HUMAN (5-131): 5.82e-58: 177: 60.94
+	Hs
		617974 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		H2AJ_HUMAN (5-131): 1.03e-57: 177: 60.16