HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: SPT5 (P27692)
Transcription elongation factor SPT5 (Chromatin elongation factor SPT5)
Gene: SPT5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	35102600, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 1063
+	Sc
		355809 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		SPT5_YEAST (1-1063): 0: 803: 100.00
+	Hs
		123957 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SPT5H_HUMAN (125-1060): 0: 781: 23.54
+	Hs
		123904 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		SPT5H_HUMAN (125-1060): 0: 781: 23.54
+	Hs
		707767 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		MDN1_HUMAN (30-582): 8.01e-09: 62.3: 10.61