HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30104407, 19661920
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031298 - replication fork protection complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 933
+	Sc
		355817 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		MCM4_YEAST (1-933): 0: 953: 100.00
+	Hs
		708456 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		MCM4_HUMAN (30-926): 0: 826: 41.57
+	Hs
		707531 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		MCM4_HUMAN (30-926): 0: 826: 41.57
+	Hs
		832512 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		617935 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832673 H2B1M_HUMAN (7-128): 9.18e-47: 148: 69.36		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832497 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832624 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		708674 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		617930 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708749 H2B1M_HUMAN (7-128): 9.18e-47: 148: 69.36		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708664 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708719 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		707532 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		1055566 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		MCM6_HUMAN (170-909): 0: 696: 27.72
+	Hs
		1055603 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		MCM6_HUMAN (170-909): 0: 696: 27.72
+	Sc
		355816 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		MCM5_YEAST (189-905): 0: 679: 26.92
+	Sc
		355815 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		MCM2_YEAST (23-849): 0: 677: 25.49
+	Hs
		708933 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		MCM7_HUMAN (186-904): 0: 646: 29.50
+	Hs
		707533 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		MCM7_HUMAN (186-904): 0: 646: 29.50