HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: SAS3 (P34218)
Histone acetyltransferase SAS3 (EC 2.3.1.48) (Something about silencing protein 3)
Gene: SAS3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	25473596, 16923967, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 831
+	Sc
		355855 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		SAS3_YEAST (1-831): 0: 1474: 100.00
+	Dm
		355268 H2B_DROME (8-128): 2.21e-45: 145: 67.77		TIP60_DROME (248-573): 1.04e-143: 436: 41.10
+	Hs
		1087406 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT8_HUMAN (223-574): 4.81e-143: 431: 36.08
+	Mm
		1145470 H2B2B_MOUSE (7-128): 7.21e-47: 149: 70.97		KAT5_MOUSE (260-573): 2.72e-141: 429: 42.99
+	Hs
		617961 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		KAT6B_HUMAN (210-577): 2.12e-129: 429: 35.58
+	Hs
		918694 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		KAT8_HUMAN (223-574): 4.81e-143: 431: 36.08
+	Hs
		1087295 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT6B_HUMAN (210-577): 2.12e-129: 429: 35.58
+	Hs
		1264460 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		KAT6B_HUMAN (210-577): 2.12e-129: 429: 35.58
+	Hs
		707704 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		KAT5_HUMAN (260-573): 2.72e-141: 429: 42.99
+	Hs
		918578 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		KAT5_HUMAN (260-573): 2.72e-141: 429: 42.99
+	Hs
		1231219 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		KAT5_HUMAN (260-573): 2.72e-141: 429: 42.99
+	Sc
		356037 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		ESA1_YEAST (226-579): 4.05e-141: 426: 36.46
+	Hs
		1129832 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		KAT6A_HUMAN (275-579): 8.81e-127: 421: 41.64
+	Sc
		355677 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		ESA1_YEAST (226-579): 4.05e-141: 426: 36.46
+	Hs
		617965 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		KAT6A_HUMAN (275-579): 8.81e-127: 421: 41.64
+	Hs
		1087309 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT6A_HUMAN (275-579): 8.81e-127: 421: 41.64
+	Hs
		309661 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		KAT7_HUMAN (248-574): 1.84e-136: 420: 40.37
+	Hs
		309707 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT7_HUMAN (248-574): 1.84e-136: 420: 40.37
+	Hs
		309686 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		KAT7_HUMAN (248-574): 1.84e-136: 420: 40.37
+	Hs
		1273427 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		KAT5_HUMAN (260-573): 2.72e-141: 429: 42.99