HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	37968396, 22199229, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 686
+	Sc
		355860 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		BDF1_YEAST (1-671): 6.18e-147: 445: 100.00
+	Hs
		1087422 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46
+	Sc
		355980 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RSC4_YEAST (105-686): 4.92e-54: 198: 15.22
+	Hs
		1087228 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PB1_HUMAN (91-664): 4.19e-38: 154: 11.97
+	Hs
		1087308 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		CBP_HUMAN (249-418): 7.85e-37: 150: 25.73
+	Hs
		319121 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53
+	Hs
		319214 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53
+	Hs
		617986 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56
+	Hs
		1087475 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56
+	Sc
		356027 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		BDF2_YEAST (17-331): 4.8e-28: 121: 16.35
+	Hs
		1066994 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60
+	Hs
		631445 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18
+	Hs
		631358 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18
+	Hs
		244513 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71
+	Hs
		244752 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71
+	Hs
		244011 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71
+	Hs
		1087293 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PHIP_HUMAN (314-685): 3.59e-20: 97.9: 12.30
+	Hs
		1274470 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		BAZ2B_HUMAN (307-420): 7.75e-13: 74.3: 39.47
+	Hs
		998782 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		EP300_HUMAN (303-417): 1.53e-09: 63.5: 37.61
+	Sc
		355988 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		GCN5_YEAST (124-255): 2.17e-09: 62: 31.82