HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: ESA1 (Q08649)
Histone acetyltransferase ESA1 (EC 2.3.1.48) (Protein 2-hydroxyisobutyryltransferase ESA1) (EC 2.3.1.-) (Protein acetyltransferase ESA1) (EC 2.3.1.-) (Protein crotonyltransferase ESA1) (EC 2.3.1.-)
Gene: ESA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	23109429, 20810648, 21179020
Identification Methods	pull down, enzymatic study, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 445
+	Sc
		356037 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		ESA1_YEAST (1-445): 0: 608: 100.00
+	Hs
		1087406 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT8_HUMAN (22-434): 0: 525: 40.10
+	Hs
		918694 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		KAT8_HUMAN (22-434): 0: 525: 40.10
+	Hs
		309661 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		309707 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		309686 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		617961 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		KAT6B_HUMAN (93-439): 6.53e-158: 493: 41.43
+	Hs
		1087295 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT6B_HUMAN (93-439): 6.53e-158: 493: 41.43
+	Hs
		1264460 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		KAT6B_HUMAN (93-439): 6.53e-158: 493: 41.43
+	Hs
		1129832 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		617965 H2B1O_HUMAN (7-128): 2.09e-46: 148: 70.97		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		1087309 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Sc
		355855 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		SAS3_YEAST (91-439): 1.16e-131: 401: 34.53
+	Dm
		355268 H2B_DROME (8-128): 2.21e-45: 145: 67.77		TIP60_DROME (1-127): 2.12e-22: 101: 20.61
+	Mm
		1145470 H2B2B_MOUSE (7-128): 7.21e-47: 149: 70.97		KAT5_MOUSE (17-165): 4.14e-19: 91.7: 27.27
+	Hs
		707704 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		KAT5_HUMAN (17-165): 3.96e-19: 91.7: 27.27
+	Hs
		918578 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		KAT5_HUMAN (17-165): 3.96e-19: 91.7: 27.27
+	Hs
		1087454 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		MO4L1_HUMAN (20-180): 8.97e-13: 71.2: 11.50
+	Hs
		666487 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		ARI4A_HUMAN (31-171): 6.52e-09: 60.5: 16.88
+	Hs
		666475 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		ARI4A_HUMAN (31-171): 6.52e-09: 60.5: 16.88