HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	37968396, 24034245, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 471
+	Sc
		356054 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Hs
		1129867 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		1087493 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		707796 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		918777 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		886220 H2B1D_HUMAN (7-128): 1.99e-45: 145: 70.16		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		1087495 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		707797 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		918779 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		1231264 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		1282982 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Hs
		1282984 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Sc
		355997 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Dm
		355271 H2B_DROME (8-128): 2.21e-45: 145: 67.77		RUVB1_DROME (10-448): 0: 622: 40.18
+	Sc
		355620 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		RUVB1_YEAST (8-448): 0: 624: 41.10