HitPredict

Interactor 1: H2B2 (P02294)
Histone H2B.2
Gene: HTB2

Interactor 2: DPOE (P21951)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POL2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	11805826, 23499444, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 2222
+	Sc
		355347 H2B1_YEAST (1-131): 4.04e-44: 142: 96.95		DPOE_YEAST (1-2222): 0: 2941: 100.00
+	Hs
		658344 H2B1C_HUMAN (7-129): 9.01e-47: 148: 70.40		DPOD1_HUMAN (1-637): 3.42e-144: 481: 14.67
+	Hs
		456106 H2B1C_HUMAN (7-129): 9.01e-47: 148: 70.40		DPOLA_HUMAN (89-635): 1.09e-97: 351: 12.42
+	Sc
		355758 H2B2_YEAST (1-131): 1.08e-45: 146: 100.00		DPOLA_YEAST (231-637): 1.77e-77: 287: 10.92
+	Sc
		355319 H2B1_YEAST (1-131): 4.04e-44: 142: 96.95		DPOLA_YEAST (231-637): 1.77e-77: 287: 10.92
+	Hs
		238311 H2B2F_HUMAN (7-129): 8.57e-48: 151: 70.40		REV3L_HUMAN (265-637): 1.88e-71: 269: 11.14